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Bone Restore

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  • Bone Restore

Bone Restore

Regular Price: NZ$62.00

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Bone Restore

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Throughout life, cells known as osteoblasts construct bone matrix and fill it with calcium. At the same time, osteoclasts work just as busily to tear down and resorb bone. This fine balance is regulated by many factors, including systemic hormones and cytokines. Bone mass reaches its peak by the middle of the third decade of life and plateaus for about ten years, during which time bone turnover is constant, with bone formation approximately equaling bone resorption.1

Details

As our bodies age, this fine balance is lost. As the relative hormone levels shift in midlife — more drastically in women than in men — the osteoclasts gain the upper hand and bone mass begins to dwindle. Some bone is already being lost by the time women reach menopause, but the rate of loss can increase up to tenfold during the first five years after menopause.2,3

Bone density loss is not just associated with calcium deficiency, but also with an insufficient intake of a host of other nutrients4-11 including magnesium10,11 and vitamin D3.12,13 In order for calcium to help maintain healthy bones, adequate amounts of vitamin D3, zinc,14,15 magnesium,16 manganese,8 and other nutrients should be available so that calcium and phosphorus can be incorporated into the bone matrix. Additionally, many forms of calcium are not particularly well absorbed.17-19

Calcium is the most abundant mineral in the body ... primarily found in the bones and teeth. In bone formation, calcium forms crystals that provide strength to maturing bone. Peak bone mass is usually achieved when people are in their 20s.

While loss of bone mineral density is more commonly experienced by women, aging men can also have this issue.20 Both men and women may experience significant deficits of magnesium if they do not supplement. Bone Restore now contains magnesium citrate, which is one of the most absorbable forms of magnesium. Magnesium is not only needed to maintain strong bones, but it is critical to promoting a healthy vascular system.21,22 In fact, magnesium is critical for facilitating hundreds of enzymatic reactions that our bodies require to maintain optimal health.23,24

To overcome the impediments that preclude aging adults from achieving optimal calcium status, Life Extension offers a proprietary comprehensive mineral formula called Bone Restore which has been designed to support healthy bone density and strength. Bone Restore provides 1200 milligrams of elemental calcium from three different forms, along with the critically important nutrients magnesium,16 boron,4,25-27 zinc,7,14,15 silicon,28-30 manganese8 and vitamin D312,13 needed for healthy bones.

In fact, the boron in this formula, called FruiteX B® OsteoBoron®, is a boron/carbohydrate complex, similar to what is found in fruits and vegetables and is more bioavailable than boron citrate. Scientific research has established the beneficial effects of boron on the strength of bones and joints.4,31-34

One reason why aging people experience bone mineral density loss even though they are taking calcium supplements is that they may not be absorbing enough elemental calcium. Bone Restore provides calcium in capsule form to ensure that it breaks down fully in the digestive tract.

Calcium and other minerals are best not taken with fiber, because fiber can interfere with their absorption.35-37 There is evidence that calcium from supplements and dairy foods may inhibit iron absorption, although it has been very difficult to distinguish between the effects of calcium on iron absorption versus other inhibitory factors, such as phytate.38-40

Calcium supplements are best taken with meals. They should always be taken with a full glass of water, juice, or other liquid to enhance solubility.41 If calcium-containing formulas are taken only once daily, they may be best taken in the evening.42

References
1. Acta Obstet Gynecol Scand. 1993 Apr;72(3):148-56.
2. Eur J Clin Invest. 1988 Oct;18(5):529-34.
3. Bone. 2001 Mar;28(3):327-31.
4. Magnes Trace Elem. 1990;9(2):61-9.
5. Curr Pharm Des.2003;9(32):2687-704.
6. Ann Nutr Metab. 2002;46(6):249-53.
7. J Int Med Res. 2007 Sep-Oct;35(5):692-5.
8. J Nutr. 1994 Jul;124(7):1060-4.
9. Crit Rev Food Sci Nutr. 2006;46(8):621-8.
10. Magnes Res. 1993 Jun;6(2):155-63.
11. J Reprod Med. 1990 May;35(5):503-7.
12.J Clin Endocrinol Metab. 2010 Jun;95(6):2630-3.
13. Am J Clin Nutr. 1995 Mar;61(3 Suppl):638S-45S.
14. Ann Nutr Metab. 2009;54(3):218-26
15. Toxic Sci. 2006 Jul;92(1):286-94
16. PDR for Nutritional Supplements, 1st ed. Montvale, NJ: Medical Economics Co.; 2001:288-95.
17. J Nutr Sci Vitaminol (Tokyo). 1999 Oct;45(5):509-17.
18. Methods Find Exp Clin Pharmacol. 1995 Sep;17(7):437-42.
19. Scand J Gastroenterol. 2010;45(2):133-8.
20. Osteoporos Int. 2009 Jul;20(7):1175-82.
21. Congest Heart Fail. 2006 Jan-Feb;12(1):9-13.
22. Br J Sports Med. 2006 Sep;40(9): 773-8.
23. Front Biosci. 2004 May 1;9:1278-93.
24. South Med J. 2001 Dec;94(12):1195-201.
25. PDR for Nutritional Supplements, 1st ed. Montvale, NJ: Medical Economics Co.; 2001:60-3.
26. Magnes Trace Elem. 1990;9:61-9.
27. Environ Health Perspect. 1994 Nov;102 Suppl 7:59-63.
28. Bone. 2003 Feb;32(2):127-35.
29. Magnes Res. 1993 Sep;6(3):247-9.
30. Biol Trace Elem Res. 2009 Jun;128(3):239-47.
31. Environ Health Perspect. 1994 Nov;102 Suppl 7:83-5.
32. Crit Rev Food Sci Nutr. 2003;43(2):219-31.
33. Prog Food Nutr Sci. 1993 Oct-Dec;17(4):331-49.
34. Nutr Rev. 2008 Apr;66(4):183-91.
35. Am J Clin Nutr. 2010 May;91(5):1461S-1467S.
36. J Nutr Sci Vitaminol (Tokyo). 2006 Dec;52(6):402-6.
37. Am J Clin Nutr. 2010 May;91(5):1430S-1432S.
38. Institute of Medicine Washington, DC: National Academy Press, 2001. http://www.nap.edu/openbook.php?record_id=10026&page=292
39. Am J Clin Nutr. 1991 Jan;53(1):106-11.
40. Am J Clin Nutr. 1998 Jul;68(1):96-102.
41. Osteoporos Int. 1991 Feb;1(2):65-71.
42. J Clin Endocrinol Metab. 1994 Sep;79(3):730-5.

Always read the label and use as directed. If symptoms persist see your healthcare professional.

Supplement Information

Serving Size 5 capsules

Servings Per Container 30

Amount Per Serving

Vitamin D3 (as cholecalciferol)

1000 IU

Calcium (as DimaCal® dicalcium malate, TRAACS® calcium glycinate chelate, calcium fructoborate)

1200 mg

Magnesium (as magnesium citrate)

100 mg

Zinc (as zinc amino acid chelate)

2 mg

Manganese (as manganese amino acid chelate)

1 mg

Silicon [from horsetail (Equisetum arvense) extract (herb)]

5 mg

Boron (calcium fructoborate as patented Fruitex B® OsteoBoron®)

3 mg

Other ingredients: gelatin, vegetable stearate, maltodextrin.

Contains corn and rice.

Fruitex B® and OsteoBoron® are registered trademarks of VDF Futureceuticals, Inc. U.S. patent #5,962,049.
DimaCal® and TRAACS® are registered trademarks of Albion Laboratories, Inc. Malate is covered by U.S. Patent 6,706,904 and patents pending.

Dosage and Use

  • Take five capsules daily, or as recommended by a healthcare practitioner.
  • Scientific studies suggest calcium supplementation in divided doses with food in the morning and evening may yield the best results.
  • Maintaining an optimal vitamin D blood level also helps maximize calcium absorption.

Warning

Keep out of the reach of Children

Do not exceed recommended dose.

When using nutritional supplements, please consult with your Doctor if you are undergoing treatment for a medical condition or if you are pregnant or lactating.

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